{"id":55326,"date":"2019-01-12T12:26:47","date_gmt":"2019-01-12T12:26:47","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=wiki&#038;p=55326"},"modified":"2019-01-12T12:26:47","modified_gmt":"2019-01-12T12:26:47","slug":"proguanil","status":"publish","type":"wiki","link":"https:\/\/www.humanitas.net\/fr\/wiki\/ingredients-actifs-2\/proguanil\/","title":{"rendered":"Proguanil"},"content":{"rendered":"<p>Le proguanil est utilis\u00e9 pour pr\u00e9venir les infections caus\u00e9es par Plasmodium qui est responsable du paludisme.<\/p>\n<p>&nbsp;<\/p>\n<h2><\/h2>\n<h2>Qu&#8217;est-ce que le Proguanil ?<\/h2>\n<p>Le proguanil pr\u00e9vient la reproduction de certaines esp\u00e8ces de parasites du paludisme (Plasmodium falciparum et Plasmodium vivax) en inhibant l&#8217;enzyme Dihydrofolate r\u00e9ductase, dont l&#8217;activit\u00e9 est n\u00e9cessaire \u00e0 la reproduction des parasites.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2>Comment doit-on prendre le Proguanil ?<\/h2>\n<p>Le proguanil est d\u00e9livr\u00e9 uniquement sur ordonnance, sous forme de comprim\u00e9s et habituellement en association avec un autre m\u00e9dicament.<\/p>\n<p>&nbsp;<\/p>\n<p>Il est g\u00e9n\u00e9ralement recommand\u00e9 de le prendre apr\u00e8s un repas, avec un verre d&#8217;eau. La dose est variable selon le patient. Pour \u00eatre efficace, le traitement doit \u00eatre amorc\u00e9 au moins 24 heures avant l&#8217;exposition potentielle au plasmodium.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2>Les effets secondaires associ\u00e9s au Proguanil<\/h2>\n<p>Parmi les effets n\u00e9fastes possibles, mentionnons les suivants :<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>Diarrh\u00e9e<\/li>\n<li>Maux de t\u00eate<\/li>\n<li>Perte d&#8217;app\u00e9tit<\/li>\n<li>Ulc\u00e8res ou plaies dans la bouche<\/li>\n<li>Naus\u00e9es<\/li>\n<li>Perte de cheveux temporaire<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>Vous devez imm\u00e9diatement contacter un m\u00e9decin si vous suffrez de l\u2019un des symt\u00f4mes suivants :<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>\u00c9ruption cutan\u00e9e<\/li>\n<li>D\u00e9mangeaisons de la peau<\/li>\n<li>Douleurs abdominales ou thoraciques<\/li>\n<li>Sang dans l&#8217;urine<\/li>\n<li>Douleurs lombaires<\/li>\n<li>Douleur ou sensation de br\u00fblure pendant la miction<\/li>\n<li>Vomissements<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><\/h2>\n<h2>Contre-indications et mises en garde associ\u00e9es \u00e0 l&#8217;utilisation du Proguanil<\/h2>\n<p>De plus, avant de commencer le traitement, il est important d&#8217;en informer votre m\u00e9decin si :<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>Vous \u00eates allergique \u00e0 la substance active, \u00e0 d&#8217;autres composants ou \u00e0 d&#8217;autres m\u00e9dicaments ou aliments<\/li>\n<li>Vous prenez d&#8217;autres m\u00e9dicaments, rem\u00e8des \u00e0 base de plantes m\u00e9dicinales et suppl\u00e9ments, en particulier l&#8217;orthioglucose, le dicoumarol, la warfarine et la chloroquine<\/li>\n<li>Vous souffrez (ou avez souffert) de probl\u00e8mes r\u00e9naux<\/li>\n<li>Vous avez re\u00e7u le vaccin contre la typho\u00efde ou pr\u00e9voyez d\u2019en recevoir<\/li>\n<li>Vous \u00eates enceinte ou vous allaitez<\/li>\n<\/ul>\n","protected":false},"author":11,"featured_media":0,"template":"","wiki-categories":[2224],"wiki-types":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.7.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Proguanil - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/fr\/wiki\/ingredients-actifs-2\/proguanil\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Proguanil - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Le proguanil est utilis\u00e9 pour pr\u00e9venir les infections caus\u00e9es par Plasmodium qui est responsable du paludisme. &nbsp; Qu&#8217;est-ce que le Proguanil ? 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