{"id":51904,"date":"2018-06-19T07:52:51","date_gmt":"2018-06-19T07:52:51","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=wiki&#038;p=51904"},"modified":"2018-06-19T07:52:51","modified_gmt":"2018-06-19T07:52:51","slug":"etakrinska-kiselina","status":"publish","type":"wiki","link":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/etakrinska-kiselina\/","title":{"rendered":"Etakrinska kiselina"},"content":{"rendered":"<p>Etakrinska kiselina predstavlja diuretike sa signifikantnim inhibitornim dejstvom na reapsorpciju elektrolita pogotovo na nivou ascedentnog nivoa Henleove petlje. Mo\u017ee se primenjivati peroralnim putem ili u vidu intravenske aplikacije kod te\u017eih oblika edematoznih stanja koji ne reaguju adekvatno na primenu drugih diuretika.<\/p>\n<p>&nbsp;<\/p>\n<p>Ta\u010dan mehanizam dejstva jo\u0161 uvek je nepoznat, ali se smatra da deluje putem inhibicije reapsorpcije natrijumovih jona\u00a0 (Na +) du\u017e nefrona, interreaguju\u0107i sa sulfihidrilnim grupama \u0107elijskih proteina.<\/p>\n<h2><\/h2>\n<h2>\u0160ta je Etakrinska kiselina?<\/h2>\n<p>Osnovna funkcija etakrinske kiseline jeste sli\u010dna mehanizmu dejstva diuretika, sa stimulacijom produkcije i eliminacije urina. Naro\u010dito se ovaj lek primenjuje kod pacijenata sa te\u017eim formama edema koji ne reaguje adekvatno na\u00a0 primenu drugih diuretika.<\/p>\n<p>&nbsp;<\/p>\n<h2>Kako se primenjuje Etakrinska kiselina ?<\/h2>\n<p>&nbsp;<\/p>\n<p>Etakrinska kiselina\u00a0 dostupna je u vidu peroralne i intravenske upotrebe.<\/p>\n<p>Ne\u017eeljeni efekti primene Etakrinske ksieline<\/p>\n<p>&nbsp;<\/p>\n<p>Naj\u010de\u0161\u0107i ne\u017eelejni efekti podrazumevaju:<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>Elektrolitni disbalans: karakteri\u0161e se pojavom mu\u010dnine ili povra\u0107anja, slabosti ili malaksalosti, hipotenzije, \u017ee\u0111i, suvih usta, mi\u0161i\u0107nih gr\u010deva, pomena raspolo\u017eenja, mentalne konfuzije, hiponatrijemija, hiperkalcijemije, hipoglikemije, hiperurikemije<\/li>\n<li>Krvnih diskrazija (patolo\u0111ka stanja ili poreme\u0107aji elementa krvi)<\/li>\n<li>Gastroointestinalni poreme\u0107aji: mu\u010dnina, povra\u0107anje, disfagija, abdominalni bol<\/li>\n<li>Sistemski poreme\u0107aji: glavobolja, groznica<\/li>\n<li>Poreme\u0107aji bubre\u017ene funkcije<\/li>\n<li>Poreme\u0107aji vestibularnog sistema: tinitus, o\u0161te\u0107enje sluha, vertigo<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Kontraindikacije i mere opreza udru\u017eene sa primenom Etakrinske kiseline<\/h2>\n<p>&nbsp;<\/p>\n<p>Primena etakinske kiseline kontraindikovana je kod trudnica ili dojilja kao i dece uzrasta mla\u0111eg od dve godine.\u00a0 \u0160ta vi\u0161e,\u00a0 etkainska kiselina primenjuje se obazivo kod osoba\u00a0 sa uznapredovalom cirozom jetre. Kao i druge grupe diuretika, etakrinska kiselina mo\u017ee precipitari nastanak hepati\u010dne kome.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"author":11,"featured_media":0,"template":"","wiki-categories":[1795],"wiki-types":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.7.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Etakrinska kiselina - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/etakrinska-kiselina\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Etakrinska kiselina - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Etakrinska kiselina predstavlja diuretike sa signifikantnim inhibitornim dejstvom na reapsorpciju elektrolita pogotovo na nivou ascedentnog nivoa Henleove petlje. 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