Dr. Paolo Antonio Pagnotta, educated in Rome, has been practicing heart surgery since 1989, including at Humanitas since 2002. He performs over 1700 surgeries annually, and specializes in:

  • Percutaneous Coronary Angioplasty: approximately 8,000 procedures performed during career;
  • Percutaneous peripheral angioplasty: approximately 3,000 procedures performed;
  • Percutaneous transcatheter aortic valve implantation (TAVI): 850+ procedures performed.

More specifically, the specialist practices the following:

– Complex coronary interventions with minimally invasive (radial) approach: treatment of multi-vessel coronary disease, common trunk, degenerated aorto-coronary by-pass with the use of anti-embolic protection systems, calcified stenosis with the use of rotational atherectomy (Rotablator).

– Placement of all the latest antiproliferative drug eluting stents; bioresorbable stents; use of invasive morphological and functional assessment techniques of the coronary plaque (IVUS and FFR).

– Treatment of degenerated valve bioprostheses; degenerated pulmonary ducts. Implantation of devices for occlusion of the left auricle in patients with atrial fibrillation and for occlusion of patent foramen ovale (PFO) and atrial defects (DIA).

– Peripheral vascular intervention: angioplasty and stenting of the carotid and supra-aortic vessels with protective devices of the cerebral circulation (filters and MOMA). Stent angioplasty of the renal vessels and iliac-femoral axes.

– Surgical treatment of resistant arterial hypertension, with denervation of the renal vessels.

Dr. Pagnotta’s research interests include: coronary circulation, implantation and imaging techniques for the endovascular treatment of degenerative and functional aortic valvular diseases, and antithrombotic therapy in acute coronary syndromes.

Dr. Pagnotta continuously passes his expertise to new generations of heart surgeons, teaching both at the Humanitas University, in other institutions in Italy, and abroad. For instance, the surgeon has been a guest lecturer at the International Interventional Cardiology Course in Paris from 2010 to 2019.