The Department of General Medicine and Hepatology is a reference center for liver diseases and complex cases of internal medicine, also housing the Center for Research and Treatment of Autoimmune Liver Diseases. The Department specialists see almost 4,000 patients each year.

The main interests of the Operating Unit, from a clinical research perspective, are aimed at the diagnosis and treatment of liver diseases such as:

  • Autoimmune diseases (primary bilary cirrhosis, primary sclerosing cholangitis, autoimmune hepatitis) for which the Unit is recognized internationally
  • Chronic hepatitis (viral and metabolic) and cirrhosis complications
  • Primary liver cancer (hepatocellular carcinoma) and bile ducts(cholangiocarcinoma)

As part of the Operating Unit, elective patients both with complex clinical problems or critical problems, are hospitalized. Many activities take place on an outpatient and day hospital basis. Often, the complexity derives from the simultaneous presence of several diseases for which an individualized approach is required, both systematic and unitary, in particular for therapeutic formulation.

The Unit includes professionals such as research nurses and data managers, who work in teams with doctors to carry out clinical research aimed at identifying new therapy for several liver diseases, especially for autoimmune diseases and viral infections.

The Operating Unit of General Medicine and Hepatology and the Center for Autoimmune Liver Diseases are also equipped with a Hepatobiliary Immunopathology Laboratory, where immunologic tests are performed and projects on basic research and translational research are pursued, especially for immune-mediated liver diseases and liver tumors.