The Unit of Rheumatology and Clinical Immunology at the direction of the university is interested in problems with joints, muscles, bones and systemic autoimmune diseases through outpatient, day hospital and inpatient hospitalization.

The unit deals with the diagnosis and treatment of:

  • Osteoarticular systemic diseases – such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Reiter's syndrome, gout, polymyalgia rheumatica, rheumatic fever, Paget’s disease, osteoarthritis, osteoporosis as well as periarthritis of the shoulder, carpal tunnel syndrome, tendonitis, and fasciitis.
  • Systemic autoimmune diseases, in which there is often no involvement of bones and joints (systemic lupus erythematosus, scleroderma, Sjögren's syndrome, mixed connective tissue disease and syndromes "overlap", antiphospholipid syndrome, polymyositis and dermatomyositis).

The unit also pays special attention to the treatment of Raynaud's phenomenon, and vasculitis (e.g. Horton arteritis, Behcet's disease, Takayasu's arteritis). The Unit has a long experience in the study and treatment of Raynaud's phenomenon and scleroderma, in particular in the treatment of trophic skin lesions with prostanoids (therapy performed with hospitalization, generally in Day Hospital) and inhibitors of endothelin, pulmonary hypertension, serious complications of the disease that are now well controlled with new therapies and in the interest of the gastro-esophageal system.

The Unit of Rheumatology at Humanitas is authorized to dispense "biologics" active in various forms of arthritis and it has recently started a clinic dedicated to patients being treated with these drugs.

The Rheumatology Unit at Humanitas has a clinic dedicated to Raynaud's phenomenon and scleroderma; two surgeries are currently dedicated to osteometabolic diseases (osteoporosis, Paget’s disease); one, in collaboration with Oncology, which evaluates the risk of osteoporosis in women with breast cancer from an osteometabolic point of view. The second, a clinic dedicated to osteoporosis and bone diseases. There are also clinics dedicated to instrumental procedures: capillaroscopy, surveys necessary for patients with Raynaud's phenomenon and scleroderma, joint ultrasound, arthrocentesis, articular infiltration and joint infiltration under ultrasound guidance.

Finally, the Unit is an authorized center for the diagnosis and treatment of rare diseases:

dermatopolymyositis, polymyositis, mixed connective tissue disease, eosinophilic fasciitis, undifferentiated connective tissue disorders.