Rosiglitazone is used in combination with diet and exercise to treat type 2 diabetes.


What is Rosiglitazone?


Rosiglitazone acts by increasing the sensitivity of cells to insulin.


How should Rosiglitazone be taken?


Rosiglitazone is administered orally, in the form of tablets, alone or in combination with other anti-diabetic agents.


Side effects associated with Rosiglitazone


Rosiglitazone may cause or worsen heart failure, increase the risk of heart attack as well as fractures. It can also stimulate ovulation.


Among the other possible side effects are included:


  • Flu-like symptoms
  • Headache


It is important to contact a doctor immediately if taking Rosiglitazone triggers any of the following symptoms:


  • Rash
  • Itching
  • Swelling of face, eyes, lips, tongue or throat
  • Difficulty breathing
  • Tightness in the chest
  • Unusual hoarseness
  • Vision problems
  • Rapid heartbeat
  • Feeling faint or lightheaded
  • Numbness of an arm or a leg
  • Skin redness, swelling or peeling
  • Strong headaches
  • Severe stomach pain or severe vomiting
  • Symptoms of a heart failure
  • Liver problems
  • Hypoglycemia
  • Bone ache
  • Fatigue or unusual weakness


Contraindications and warnings associated with the use of Rosiglitazone


Rosiglitazone is contraindicated in case of heart failure, type 1 diabetes or diabetic ketoacidosis. It should also not be taken with insulin.


Rosiglitazone may compromise the ability to drive or operate hazardous machinery; this effect can be aggravated by alcohol and certain drugs.


Moreover, before starting treatment, it is important to tell your doctor if:


  • You have any allergies to the active substance, its excipients, other medicines, foods, or any other substance
  • You are taking other medications, herbal remedies and supplements, in particular drugs against pressure or high cholesterol, medicines for heart failure or to prevent heart disease or stroke, insulin, other anti-diabetic agents, rifamycins, gemfibrozil or anticoagulants
  • You took troglitazone
  • You suffer (or have suffered) from liver problems or jaundice, diabetic ketoacidosis, stroke, heart disease, macular edema or other problems with your eyes and sight, anemia, fluid retention and edema
  • You are pregnant or breastfeeding


You must inform doctors, surgeons and dentists about ongoing treatment with Rosiglitazone prior to any procedure.