The action of Bromhexine is based on the depolymerization of the proteins that form the structure of the mucous secretions carrier (mucoproteins), facilitating expectoration of the same and alleviating cough. Bromhexine also stimulates ciliary motility of the respiratory tract, thus facilitating the elimination of mucus.
What is Bromhexine?
Bromhexine is the derivative of vascicina, an alkaloid that is extracted from the leaves of an Indian herb, Indian Adatoda, known for its bronchodilator and antitussive activity.
The action mainly carried out by Bromhexine is mucolytic: therefore, it favors the elimination of mucus that stagnates the airways. The main use of this active principle is against cough and all diseases of the respiratory system in general characterized by disorders of secretion.
How should Bromhexine be taken?
Bromhexine is usually administered orally (in the form of syrup).
Side effects associated with Bromhexine
The use of Bromhexine is usually more than well tolerated. The only reported adverse effects are very rare and may include:
- Various gastrointestinal disorders
- Allergic reactions affecting the skin or mucous membranes
Contraindications and warnings associated with the use of Bromhexine
Similar to other mucolytics, Bromhexine can also damage the gastric mucosa; therefore, it is recommended to take it on a full stomach and be extra cautious with patients with history of gastric ulcers.
From studies to date, Bromhexine is safe in pregnancy, although it is always better to take it upon medical indication. Furthermore, Bromhexine accumulates in breast milk, and without evidence to suggest the possible effects on the unborn child, its administration is not recommended during breastfeeding unless the potential benefit to the mother outweighs the potential health risks to the infant.