Conivaptan is used to treat conditions in which blood sodium levels are too low.


What is Conivaptan?

Conivaptan works by increasing fluid excretion from the body. In this way, it helps to normalize blood sodium levels.


How should Conivaptan be taken?

Conivaptan is administered intravenously via injections.


Side effects associated with Conivaptan

Conivaptan can alter blood sugar levels in the body.


Among the other possible side effects of conivaptan include the following:


  • Constipation
  • Diarrhea
  • Dry mouth
  • Headache
  • Increased thirst
  • Nausea
  • Insomnia
  • Vomiting


It is important to contact a doctor immediately if you experience:


  • Rash
  • Urticaria
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips or tongue
  • Bloody urine
  • Confusion
  • Drowsiness
  • Fast or irregular heartbeat
  • Fever
  • Decreased or painful urination
  • Excessive sweating
  • Behavioral or mood changes
  • Muscle pain, weakness or cramps
  • Pain, soreness, redness or swelling at the injection site
  • Rapid breathing
  • Severe or persistent dizziness
  • Severe or persistent thirst
  • Tremors
  • Unusual fatigue or weakness
  • White patches in the mouth


Contraindications and warnings associated with the use of Conivaptan

Conivaptan is contraindicated in case of hypovolemia, severe kidney problems or difficult urination. It is also prohibited to take this medication if you are also taking certain azole antifungals, certain antibiotics or HIV protease inhibitors.


The drug can impair the ability to drive or operate hazardous machinery. This side effect can be aggravated by alcohol or other medications. High temperatures, strenuous physical exercise and fever can all increase dizziness caused by the medication. For these reasons, it is advisable to get up slowly from a lying or seated position (especially in the morning).

Before starting treatment with conivaptan, it is important to tell your doctor if:


  • You have any allergies to the active substance, its excipients or to any other drugs, food or various substances
  • You are taking any other medications, herbal remedies or supplements. Mentioning in particular:  azole antifungals, HIV protease inhibitors, macrolides, nefazodone, telithromycin, amlodipine, benzodiazepines, digoxin, and HMG-CoA reductase
  • You are suffering (or have suffered) from congestive heart failure, liver problems or kidney problems
  • You do not follow a nutritional diet
  • You are suffering (or have suffered) from alcohol dependence
  • You are pregnant or breast-feeding