Dantrolene is used to treat malignant hyperthermia, which is a condition that causes a fast rise in body temperature.  It can also be used to prevent this type of problem before or after undergoing surgery with general anesthesia.


What is Dantrolene?

Dantrolene works by restoring normal levels of calcium in the muscles. In this way, it helps prevent or reduce very high body temperature.


How should Dantrolene be taken?

Dantorlene is administered orally or intravenously via injections.


Side effects associated with Dantrolene

Dantrolene can cause severe liver problems.

Among the other possible side effects of Dantrolene include the following:


  • Lower grip force
  • Dizziness
  • Drowsiness
  • Redness
  • Headache
  • Nausea
  • Feeling faint or lightheaded
  • Voice changes
  • Weakness


It is important to contact a doctor immediately if you experience:


  • Rash
  • Urticaria
  • Itch
  • Difficulty breathing
  • Tightness or chest pain
  • Swelling of the mouth, face, lips or tongue
  • Inflammation of blood vessels
  • Suffocation
  • Difficulty swallowing
  • Shallow breathing
  • Shortness of breath
  • Liver problems


Contraindications and warnings associated with the use of Dantrolene

Dantrolene can compromise the ability to drive or operate hazardous machinery. This side effect can be exacerbated by alcohol and some drugs .


Before starting treatment with Dantrolene, it is important to tell your doctor if:


  • You have any allergies to the active substance, its excipients or to any other drugs or food
  • You are taking any other medications, herbal remedies or supplements. Mentioning in particular:  muscle relaxants, estrogens, drugs that can damage the liver, psychotropic drugs, or certain calcium antagonists
  • You are suffering (or have suffered) from serious heart problems, lung problems, respiratory problems or a family history of liver disorder
  • You are pregnant  or breast-feeding


 It is important to inform physicians, surgeons or dentists of any ongoing treatment with dantrolene.