Droxidopa is used to treat dizziness, lightheadedness and fainting associated neurogenic orthostatic hypotension. It is also used to treat individuals with conditions of the nervous system that can cause low blood pressure such as Parkinson’s disease and multiple system atrophy.


What is Droxidopa?

Droxidopa is an amino acid precursor. It works by constricting the blood vessels, thus increasing blood pressure.


How should Droxidopa be taken?

Droxidopa is typically administered orally, three times per day. During treatment, the doctor may change the previously prescribed dose for better results.  


Side effects associated with Droxidopa

Among the possible side effects of droxidopa include the following:


  • Headache
  • Dizziness
  • Nausea
  • Fatigue


It is important to contact a doctor immediately if you experience:


  • Rash
  • Urticaria
  • Itch
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips, throat or tongue
  • Severe dizziness or lightheadedness
  • Fever
  • Confusion
  • Painful or burning sensation while urinating
  • Extremely high blood pressure
  • Severe muscle stiffness
  • Excessive sweating
  • Irregular heartbeat
  • Tremors
  • feeling faint


Contraindications and warnings associated with the use of Droxidopa

Before starting treatment with droxidopa, it is important to tell your doctor if:


  • You have any allergies to the active substance, its excipients or to any other drugs (especially aspirin), food and various substances (such as yellow food coloring)
  • You are taking any other medications, herbal remedies or supplements
  • You are suffering (or have suffered) from heart disease, high blood pressure, kidney disease, or asthma
  • You have recently suffered from a heart attack or stroke
  • You are pregnant or breast-feeding


Droxidopa can increase blood pressure even while you are lying down. For this reason, it is advisable to keep your head slightly elevated while you sleep.