Fluorouracil is primarily used to treat tumors of the colon, rectum, breast, stomach and pancreas.


What is Fluorouracil?

Fluorouracil works by interfering with the production of proteins that are needed for the growth and multiplication of cells.


How should Fluorouracil be taken?

Fluorouracil is administered directly into the vein.


Side effects associated with Fluorouracil

Fluorouracil may reduce the body’s ability to fight infections and the number of platelets in the blood. It can also increase the skin's sensitivity to the sun.


Among the other possible side effects of Fluorouracil include the following:


  • Vision problems
  • Dry skin
  • Fatigue or weakness
  • Hair loss
  • Headache
  • Pruritic
  • Loss of appetite
  • Changes in the appearance of the nails
  • Nausea


You should contact a doctor immediately if you experience:


  • Rash
  • Urticaria
  • Itch
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips, or tongue
  • Bleeding
  • Blood in urine or stool
  • Chest pains
  • Chills
  • Fever
  • Frequent diarrhea
  • Inflammation of the mouth or throat
  • Articolar pains
  • Abdominal or lower back pain
  • Pain, redness or swelling at the injection site
  • Painful urination
  • Severe vomiting
  • Sore throat
  • Sores on the tongue or lips
  • Bleeding or bruising
  • Jaundice




Contraindications and warnings associated with the use of Fluorouracil

Fluorouracil should not be taken if you are simultaneously taking sorivudine, if you are struggling with a serious infection or if you are malnourished.


Before starting treatment with fluorouracil, it is important to tell your doctor if:


  • You have any allergies to the active substance, its excipients or any other drugs or food
  • You are taking any other medications, herbal remedies or supplements. Mentioning in particular: amphotericin B, cimetidine, folic acid, alpha interferon, leucovorin, metronidazole, sorivudine, tamoxifen, diuretics, vinca alkaloids, anticoagulants, hydantoins, carbamazepine and quinolones
  • You are suffering (or have suffered) from liver or kidney problems
  • You are pregnant or breastfeeding