Ketanserin is primarily used to treat hypertension. It is also used as an alternative drug to  treat bronchospasm and it is used as a vasodilator.


What is Ketanserin?

Ketanserin is a selective serotonin receptor antagonist. More specifically, it works by interacting with 5-HT2 serotonin receptors and inhibits vasoconstriction, bronchoconstriction and platelet aggregation. Its exact clinical effect on such interactions has not yet been identified.


How should Ketanserin be taken?

Ketanserin can be administered orally, intramuscularly via injections or intravenously via infusions.


Side effects associated with Ketanserin

Ketanserin may increase the risk of ventricular tachycardia.


Among the other possible side effects of ketanserin include the following:


  • Dizziness
  • Vision problems
  • Syncope
  • Drowsiness
  • Insomnia
  • Fatigue
  • Dry mouth
  • Feeling faint or lightheaded
  • Sedation
  • Lack of concentration
  • Gastrointestinal discomfort


It is important to contact a doctor immediately if you experience:


  • Rash
  • Urticaria
  • Difficulty breathing
  • Tightness in the chest or chest pain
  • Swelling of the mouth, face, lips or tongue


Contraindications and warnings associated with the use of Ketanserin

Ketanserin could be contraindicated in cases of second or third degree atrioventricular block. The intake of the drug can also impair the ability to drive or operate hazardous machinery.


Before starting treatment with ketanserin, it is important to tell your doctor if:


  • You have any allergies to the active substance, its excipients or to any other drugs, food or various substances
  • You are taking any other medications, herbal remedies or supplements. Mentioning in particular: antiarrhythmics or diuretics
  • You are suffering (or have suffered) from atrioventricular block or liver problems
  • You are pregnant or breast-feeding