Memantine is an NMDA receptor, which is a molecule in the synapse that binds with glutamic acid.  The latter is an amino acid that performs neurotransmitter function in the nervous system. By reducing abnormal brain activity, Memantine can help improve your logic and memory skills and slow down the process in those who are suffering from Alzheimer's.  It is, however, neither cure nor prevention drug for this neurodegenerative disease.


What is Memantine?

Memantine is used to treat the symptoms of Alzheimer's disease.


How should Memantine be taken?

Typically, Memantine is administered once a day orally, in the form of solutions, tablets or capsules for prolonged release (strictly to be taken whole).

It is likely that the doctor will initially prescribe a low dose and then gradually increase it whenever necessary.


Side effects associated with Memantine

Possible side effects of Memantine include the following:

  • Dizziness
  • Confusion
  • Aggression
  • Depression
  • Headache
  • Drowsiness
  • Diarrhea
  • Constipation
  • Nausea
  • Vomit
  • weight gain
  • body ache, especially in the back
  • cough


You should immediately contact a doctor if the drug triggers:

  • shortness of breath
  • sound or visual hallucinations


Contraindications and warnings associated with the use of Memantine

Before taking Memantine, it is important to inform your doctor:

  • If you have any allergy to the active substance, its excipients or any other medication
  • If you are taking any other medicinal products, herbal remedies or supplements. Mentioning in particular: acetazolamide, methazolamide, amantadine, dextromethorphan, potassium citrate, citric acid and sodium bicarbonate
  • If you suffer (or have suffered) from urinary tract infections, seizures, difficulty urinating, kidney disease or liver disease
  • If you are pregnant or breastfeeding

It is important to inform surgeons and dentists of any ongoing treatment with Memantine.