Pilocarpine is used to treat dry mouth caused by radiotherapy in individuals with cancer. It is also used to treat dry mouth in individuals with Sjogren's syndrome.


What is Pilocarpine?

Pilocarpine is a drug that works by increasing the secretion of saliva from the salivary glands.


How should Pilocarpine be taken?

Pilocarpine is typically administered orally. During treatment, it is advisable to drink plenty of water.


Side effects associated with Pilocarpine

Among the possible side effects of pilocarpine include the following:


  • Chills
  • Dizziness
  • Redness
  • Frequent urination
  • Nausea
  • Runny nose
  • Sweating
  • Vision problems
  • Weakness


It is important to contact a doctor immediately if you experience:


  • Rash
  • Urticaria
  • Itch
  • Difficulty breathing
  • Tightness in chest
  • Swelling of the mouth, face, lips, or tongue
  • Abdominal pain
  • Difficulty breathing
  • Heart rhythm disorders
  • Confusion
  • Excessive sweating
  • Excessive tearing
  • Headache
  • Tremors
  • Vomiting


Contraindications and warnings associated with the use of Pilocarpine

Pilocarpine can reduce the ability to drive or operate hazardous machinery. This side effect may be aggravated by alcohol and some drugs.


Before starting treatment with Pilocarpine (at least 12 weeks are required), it is important to tell your doctor if: 


  • You have any allergies to the active substance, its excipients or any other drugs or food
  • You are taking any other medications, herbal remedies or supplements. Mentioning in particular: parasympathomimetic agents, beta blockers and anticholinergic agents
  • You are suffering (or have suffered) from retinal detachment, eye infections, cardiovascular diseases, asthma, chronic bronchitis, COPD, liver or kidney disease, kidney stones or other gallbladder problems, or psychiatric illnesses
  • You are pregnant or breast-feeding