Polymyxin B is used to treat serious bacterial infections. These include Pseudomonas aeruginosa infections in the urinary tract, meninges, or in the blood.
What is Polymyxin B?
Polymyxin B interacts with some component of the outer membrane of Gram negative bacteria. In this way, it penetrates through the membrane and kills sensitive bacteria.
How should Polymyxin B be taken?
Polymyxin B can be administered intramuscularly or intravenously via infusion. This medication also exists in ophthalmic and topical forms.
Side effects associated with Polymyxin B
Prolonged or repetitive use of polymyxin b may cause a second infection.
Among the other possible side effects of polymyxin B include the following:
- Fever
- Pain at the injection site
It is important to contact a doctor immediately if you experience:
- Rash
- Urticaria
- Itch
- Difficulty breathing
- Tightness in the chest
- Swelling of the mouth, face, lips or tongue
- Changes in urination frequency
- Hard of hearing or tinnitus
- Dizziness
- Drowsiness
- Redness in the face
- Loss of coordination
- Changes in mood or behavior
- Severe headaches
- Stiff neck
- Swelling and redness at the injection site
- Tingling or numbness in the mouth, hands or feet
- Unusual weakness
- Rapid heartbeat
- Vision problems
Contraindications and warnings associated with the use of Polymyxin B
Before starting treatment with polymyxin B, it is important to tell your doctor if:
- You have any allergies to the active substance, its excipients, or to any other drugs, food and various substances
- You are taking any other medications, herbal remedies or supplements. Mentioning in particular: aminoglycosides, muscle relaxants or drugs that can cause damage to the kidneys
- You are suffering (or have suffered) from kidney problems or neuromuscular disorders
- You are pregnant or breast-feeding
Treatment with polymyxin B can compromise the ability to drive or operate hazardous machinery. This side effect can be aggravated by alcohol and certain other medications.
