Praziquantel is used for the treatment of certain worm infections, such as schistosomiasis.


What is Praziquantel?


Praziquantel is an anthelmintic. It acts by killing the worms sensitive to its action through two mechanisms: by causing severe muscle spasms and paralysis and altering the morphology of the parasite. The worms are completely destroyed in the gut or eliminated through feces.


How should Praziquantel be taken?


Praziquantel is administered orally.


Side effects associated with Praziquantel


Among the possible adverse effects of Praziquantel are included:


  • Dizziness
  • General ill feeling
  • Nausea
  • Stomach discomfort


It is important to contact a doctor immediately if taking Praziquantel triggers any of the following symptoms:


  • Rash
  • Itching
  • Swelling of face, eyes, lips, tongue or throat
  • Difficulty breathing
  • Tightness in the chest
  • Diarrhea with blood
  • Fever
  • Convulsions
  • Strong or persistent vomiting
  • Slow or irregular heartbeat


Contraindications and warnings associated with the use of Praziquantel


Praziquantel is contraindicated in case of ocular cysticercosis, during lactation, and if you are taking rifampin. Additionally, Praziquantel can compromise the ability to drive or operate hazardous machinery. This side effect can be aggravated by alcohol or taking other medicines.


Before starting treatment it is important to tell your doctor if:


  • You have any allergies to the active substance, its excipients, other medicines, foods, or any other substance
  • You are taking other medications, herbal remedies and supplements, in particular azole antifungals, cimetidine, erythromycin, anticonvulsants, chloroquine, dexamethasone and rifamycins
  • You suffer (or have suffered) from liver, kidney or heart problems, seizures or cerebral or eye cysticercosis
  • You are pregnant or breastfeeding