Promethazine is recommended for treatment of allergy symptoms such as itching, runny nose, sneezing, itchy skin, watery eyes, hives, and rashes.

It is also used in treatments for nausea, vomiting, pain after surgery or for prevention of motion sickness. Finally, it can be used as a sedative to promote sleep.

What is Prometezina?

Promethazine is a phenothiazine and works by changing the effect of certain brain molecules. In addition, it can also block histaminic action and acts as an antihistamine.

How should Prometezina be taken?

Depending on the case, Promethazine can be taken orally, rectally or through intramuscular and vein injections.

Side effects associated with Prometezina

Among the possible adverse effects are included:

  • Drowsiness
  • Dizziness
  • Tinnitus
  • Double view
  • Nervousness
  • Dry mouth
  • Fatigue
  • Insomnia

You should immediately contact a doctor if taking Prometezina triggers any of the following symptoms:

  • Tics or uncontrollable movements of the eyes, lips, tongue, face, arms or legs
  • Strong drowsiness
  • Weak or shallow breathing
  • Feeling faint
  • Confusion, agitation, hallucinations, nightmares
  • Convulsions
  • Rapid, slow or irregular heartbeat
  • Jaundice
  • Bleeding or bruising
  • Sudden illness, fever, chills , sore throat, mouth sores, red and swollen gums and difficulty swallowing
  • Severe muscle stiffness, high fever, sweating, confusion, heartbeat, tremors
  • Rash
  • Urticaria
  • Itchy skin
  • Difficult breathing
  • Chest tightness
  • Swelling of the mouth, face, lips, or tongue

Contraindications and warnings associated with the use of Promethazine

Promethazine may impair the ability to drive or operate hazardous machinery, especially when taken together with alcohol or other drugs.

The drug is contraindicated before 2 years of age.

Moreover, before starting the treatment it is important to tell your doctor if:

  • You have any allergies to the active substance, its supstances, other drugs (especially sulfites and similar medicines to prometaziona, such as: chlorpromazine, fluphenazine, thioridazine and perphenazine, prochlorperazine, thioridazine and trifluoperazine) or any food
  • You are taking other medications, herbal remedies and supplements, in particular lithium, atropine, benzatropine, belladonna, dimenhydrinate, scopolamine, blood pressure medicines, blood thinners, bronchodilators, bladder or urination drugs, MAO inhibitors, medicines against Parkinson's disease or medicines for the treatment of gastric ulcers or irritable bowel syndrome
  • You suffer (or have suffered) from asthma, COPD, sleep apnea or other breathing problems, seizures, immune system depression, glaucoma, prostatic hypertrophy or urination problems, ulcers or gastric obstruction, heart disease or high blood pressure, pheochromocytoma or hypocalcemia
  • You are pregnant or breastfeeding