Semustine is primarily used to treat brain tumors, colorectal tumors, lymphomas, and stomach cancer.


What is Semustine?

Semustine is an alkylating agent. It modifies DNA and prevents the replication and growth of cancer cells.  


How should Semustine be taken?     

Semustine is typically administered intravenously via injection.


Side effects associated with Semustine

Semustine is classified by the IARC (the International Agency for Research on Cancer) as a Group 1 carcinogen (carcinogenic to humans).


Among the possible side effects of Semustine include the following:


  • Kidney damage
  • Thrombocytopenia
  • Nausea
  • Vomiting
  • Hyperpigmentation


A possible overdose can cause:


  • Convulsions
  • Pulmonary fibrosis
  • Leukopenia
  • Optic neuritis


Contraindications and warnings associated with the use of Semustine

Before starting treatment with Semustine, it is important to tell your doctor if:


  • You have any allergies to the active ingredient , its excipients or any other drugs or food
  • You are taking any other medications, herbal remedies or supplements
  • You are suffering (or have suffered) from kidney or liver disorders
  • You are pregnant or breast-feeding