Sulindac is used to treat the pain, sensitivity, and the swelling and stiffness caused by arthrosis, rheumatoid arthritis and ankylosing spondylitis. It is also used in the treatment of shoulder pain caused by bursitis and tendinitis or against hassles associated with gouty arthritis. In some cases, it is also used to reduce the number of polyps in the colon or rectum in patients with familial adenomatous polyposis.


What is Sulindac?


Sulindac is an anti-inflammatory non-steroidal drug (NSAIDs). It acts by blocking the production of molecules at the base of the onset of pain, fever and inflammation.


How should Sulindac be taken?


Typically, Sulindac must be taken orally, twice a day in the form of tablets.

It might take more than a week before the full benefit of treatment is experienced.


Side Effects associated with Sulindac


Among the possible adverse effects of Sulindac are included:


  • Diarrhea
  • Constipation
  • Nervousness
  • Gas
  • Headache
  • Dizziness
  • Tinnitus


It is important to immediately contact a doctor if taking Sulindac triggers any of the following symptoms:


  • Weight gain
  • Fever
  • Chills
  • Cough
  • Sweating
  • Redness
  • Muscle or joint pain
  • Chest pain
  • Blisters
  • Rash
  • Itch
  • Urticaria
  • Swelling of eyes, face, lips, tongue , throat, hands, feet, ankles or calves
  • Difficulty breathing or swallowing
  • Hoarseness
  • Pallor
  • Rapid heartbeat
  • Excessive tiredness
  • Bruising or bleeding
  • Loss of appetite
  • Lack of energy
  • Stomach problems
  • Pain in the upper right abdomen
  • Flu-like symptoms
  • Jaundice
  • Turbid, colorless or bloody urine
  • Back ache
  • Difficult or painful urination
  • Vision problems (such as blurred vision)


Contraindications and warnings associated with the use of Silindac


The intake of NSAIDs, including Sulindac, can increase the risk of heart attack and stroke. It can also be associated with ulcers, bleeding and perforations in the wall of the stomach or intestines.


Moreover, before taking Sulindac you must inform your doctor if:


  • You have any allergy to the active substance, all'asprina, to any other NSAIDs or any other medicine
  • You are taking other medications, herbal remedies and supplements, remembering to mention ACE inhibitors, angiotensin II receptor antagonists, diuretics, lithium, methotrexate, probenecid and antidiabetic drugs
  • You suffer (or have suffered) from swelling in hands, feet, ankles or calves, liver or kidney disease (including calculations) or asthma (especially in case of frequent nose closed problems or nasal polyps)
  • You are pregnant or breastfeeding


You also need to inform surgeons and dentists about ongoing treatment with Sulindac prior to any procedure.