Sulpiride is used as an antidepressant, antipsychotic and it is involved in adjuvant therapy. It is used especially to treat schizophrenia by reducing the frequency and severity of its symptoms. It can also be prescribed for other psychiatric problems such as Tourette syndrome and chorea.


What is Sulpiride?

Sulpiride is an antipsychotic. It inhibits certain receptors for the neurotransmitter dopamine. In this way, it alters brain activity.


How should Sulpiride be taken?

Sulpiride is typically administered orally in the form of tablets to be taken twice a day.


Side effects associated with Sulpiride

Among the possible side effects of Sulpiride include the following:


  • Drowsiness
  • Lack of energy
  • Weight gain
  • Constipation
  • Sexual problems
  • Impotence and ejaculation problems
  • Difficulty sleeping
  • Stuffy nose
  • Confusion
  • Tarnished vision
  • Overexcitation
  • Agitation
  • Aggression
  • Change in the color of the skin or eyes
  • Increased sensitivity to the sun


 It is important to contact a doctor right away if you experience:


  • Rash
  • Urticaria
  • Itch
  • Difficulty breathing
  • Tightness in chest
  • Swelling of the mouth, face, lips, or tongue
  • High fever
  • Muscle stiffness
  • Fainting
  • Excessive sleepiness


Contraindications and warnings associated with the use of Sulpiride

Sulpiride can compromise the ability to drive or operate hazardous machinery. It can also increase sensitivity to the sun. Sulpiride should not be taken in combination with other antipsychotics.


Before starting treatment with Sulpiride, it is important to tell your doctor if:  


  • You have any allergies to the active substance, its excipients or any other drugs or food
  • You are taking any other medications, herbal remedies or supplements. Mentioning in particular: anticonvulsants, painkillers, anti-arrhythmic medications, antidepressants, antiepileptics, antihistamines, antimalarials, tranquilizers or sleeping pills
  • You are suffering (or have suffered) from agitation or aggression, kidney problems, liver or heart problems, high blood pressure, breathing problems, depression, epilepsy, prostatic hypertrophy, Parkinson’s disease, myasthenia gravis, jaundice, angle-closure glaucoma, delusions or hypomania, porphyria, bone marrow diseases, pheochromocytoma and dependent breast cancer by prolactin.
  • You are pregnant or breast-feeding


Finally, it is important to inform physicians, surgeons and dentists of any ongoing treatment with sulpiride.