Tobramycin is used to treat severe bacterial lung infection. It is also used to treat sinus infections.


What is Tobramycin?

Tobramycin kills the bacteria sensitive to its action (Gram-negative bacteria, particularly species of Pseudomonas ) by inhibiting their protein synthesis.


How should Tobramycin be taken?

Tobramycin can be administered via injection or by inhalation.  


Side effects associated with Tobramycin

Prolonged or repetitive intake of tobramycin can cause a new infection.


Among the other possible side effects of tobramycin include the following:


  • Diarrhea
  • Headache
  • Nausea
  • Vomiting
  • Pain, swelling or redness at the injection site


It is important to contact a doctor immediately if you experience:


  • Rash
  • Urticaria
  • Itch
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips or tongue
  • Clumsiness or loss of coordination
  • Confusion
  • Hearing problems
  • Decreased urination
  • Dizziness or feeling faint or lightheaded
  • Uncontrollable muscle movements
  • Persistent fever, chills or sore throat
  • Muscle weakness
  • Numbness or tingling
  • Redness, swelling, blistering or peeling of the skin
  • Ringing noises in the ears
  • Convulsions
  • Severe or persistent diarrhea
  • stomach pain or cramps
  • Bruising or bleeding
  • Vaginal dryness


Contraindications and warnings associated with the use of Tobramycin

Intake of tobramycin is contraindicated in case of treatment with ethacrynic acid, furosemide, mannitol, urea or drugs that can damage the kidneys, nervous system or lead to hearing loss.


Before starting treatment with tobramycin, it is important to tell your doctor if:


  • You have any allergies to the active substance, its excipients or to any other drugs (particularly to aminoglycoside antibiotics), substances (especially sulfites) or food
  • You are taking any other medications, herbal remedies or supplements. Mentioning in particular: cephaloridine or other cephalosporins, cisplatin, colistin, cyclosporine, fludarabine, loop diuretics, methoxyflurane, Fans, polymyxin B, vancomycin, viomycin, beta-lactams and muscle relaxants
  • You are suffering (or have suffered) from myasthenia gravis, Parkinson's disease, hearing loss or nerve or kidney disorders
  • You are suffering from severe burns or burns all throughout the body
  • You are suffering from dehydration
  • You are pregnant or breast-feeding


During treatment with tobramycin, it is recommended to drink plenty of water.


It is also important to inform physicians, surgeons and dentists of any ongoing treatment with tobramycin.