Trandolapril is used alone or in combination with other drugs to treat high blood pressure. It is sometimes prescribed in case of heart failure or infarction (to improve the chances of survival).


What is Trandolapril?

Trandolapril is an ACE inhibitor. It works by stimulating the relaxation of blood vessels. In this way, it helps reduce high levels of blood pressure. 


How should Trandolapril be taken?

Trandolapril is typically consumed orally in the form of tablets.


Side effects associated with Trandolapril

Trandolapril is dangerous for the fetus. Women who are pregnant should not take this drug as it can cause damage to the fetus or even result in death of the fetus. 


Among the possible side effects of Trandolapril include the following:


  • Cough
  • Diarrhea
  • Dizziness
  • Stomach discomfort


It is important to contact a doctor immediately if you experience:


  • Rash
  • Urticaria
  • Difficulty breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips, or tongue
  • Hoarseness
  • Chest, jaw or arm pains
  • Decreased urination
  • Increased, slow or irregular heartbeat
  • Pain, weakness or muscle cramps
  • Confusion
  • Weakness in one side of the body
  • Red, swollen, blistering or peeling skin
  • Shortness of breath
  • Difficulty speaking
  • Stomach ache
  • Sudden or severe nausea/ vomiting
  • Swelling in the hands, ankles or feet
  • Fever, chills, sore throat or other symptoms of an ongoing infection
  • Liver problems ( dark urine, loss of appetite, pale stools , severe or continuous stomach pain, jaundice )
  • Low blood pressure
  • Excessive sweating
  • Vision problems


Contraindications and warnings associated with the use of Trandolapril

Trandolapril may affect the ability to drive or operate dangerous machinery. It can also cause dizziness when standing up too quickly from a lying position. These side effects can be aggravated by alcohol, certain medications, high fever, or strenuous physical activity.

Before starting treatment with Trandolapril, it is important to tell your doctor if:


  • You have any allergies to the active substance, its excipients or any other drugs (particularly other ACE inhibitors) or food
  • You are taking any other medications, herbal remedies or supplements. Mentioning in particular:  everolimus, sirolimus, diuretics, potassium supplements, aliskiren, angiotensin receptor blockers, insulin, sulfonylurea or other drugs for diabetes, gold based drugs, NSAIDs, lithium and thiopurines
  • You are undergoing desensitization therapy for insect allergies
  • You are suffering (or have suffered) from angioedema, cardiovascular problems, bone marrow disorders, diabetes, kidney or liver disease, stroke, autoimmune diseases, dehydration, hypovolemia, high levels of potassium or low blood calcium levels
  • You have recently experienced a myocardial infarction
  • You have recently undergone a kidney transplant
  • You are maintaining a low-salt diet
  • You are dialysis or apheresis
  • You need to undergo surgery that requires anesthesia
  • You are pregnant or breast- feeding


It is important to inform doctors, surgeons and dentists of any ongoing treatment with Trandolapril.